PICCOLO DIRECTS ACTIVITY DEPENDENT F-ACTIN ASSEMBLY FROM PRESYNAPTIC ACTIVE ZONES VIA DAAM1.


Predominance of Trypanosoma rangeli infection in children from a Chagas disease endemic area in the west-shore of the Panama canal

A total of 206 serum samples from children (3-14 years old) living in the Amador County (La Chorrera District, Province of Panama) were screened by indirect immunofluorescence antibody test (IFAT) for the presence of antibodies against Trypanosoma cruzi.Positive sera here were confirmed by recombinant enzyme-linked immunosorbent assay (ELISA) and W

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A psychoeducational intervention reduces the need for anesthesia during radiotherapy for young childhood cancer patients

Abstract Background Radiotherapy (RT) has become an important treatment modality in pediatric oncology, but its delivery to young children with cancer is challenging and general anesthesia is often needed.Methods To evaluate whether a psychoeducational intervention might reduce the need for anesthesia, 223 consecutive pediatric cancer patients rece

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A network-based approach to integrate nutrient microenvironment in the prediction of synthetic lethality in cancer metabolism.

Synthetic Lethality (SL) is currently defined as a type of genetic interaction in which the loss of function of either of two genes individually has limited effect in cell viability but inactivation of both genes simultaneously leads to cell death.Given the profound genomic aberrations acquired by tumor cells, which can be systematically identified

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A Novel Tracking Strategy Based on Real-Time Monitoring to Increase the Lifetime of Dual-Axis Solar Tracking Systems

Solar tracking systems allow an increase in the use of solar energy for its conversion with photovoltaic technology due to the alignment with the sun.However, there is a compromise between tracking accuracy and the energy required to perform the movement action.Consequently, the wear of the tracker components increases, reducing its useful lifetime

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